Official UK PlayStation 2 Magazine (often abbreviated to OPS2) was launched in December 2000 as the sequel publication to the Official UK PlayStation Magazine, originally priced £4.99, to coincide with the launch of the PlayStation 2 console. Each month the magazine came with a cover-mounted playable demo DVD. It ran for 100 issues, with the last going on sale in the month of July 2008. The magazine was commonly abbreviated OPS2. It had four design changes in its lifetime: 1 to 25, 26 to 41, 42 to 89, and finally 90 to 100.

The first game to be reviewed was Tekken Tag Tournament, which received 8/10. The last game to be reviewed was SBK-08: Superbike World Championship, which earned 7/10. The magazine would go on to become the UK's best selling PlayStation 2 magazine, peaking with 197,348 readers in 2002.

In the beginning OPS2 was designed for the early adopter - encompassing hardcore gamers and previous readers crossing over from the original Official UK PlayStation Magazine. This ran from issue 1 (December 2000) to 25 (October 2002). Starting from issue 26, the magazine was set the task of attracting a more mass market, mainstream audience. This included a full redesign. From issue 34, OPS2 changed again - however this time retaining its recent redesign. In a drastic attempt to attract a more young male demographic - similar to that of the independent PlayStation magazines of the '90s - the publication decided to review readers girlfriends and their mothers; increase the babe count, even to the point of including bare breasts. It received a mixed response from readers, and failed to considerably increase the readership. In turn, the magazine featured another redesign from issue 42. OPS2 would retain this middle ground for the next three years, neither employing an overly male nor hardcore adult gamer stance. In the final year, as the PlayStation 2 entered a more family-friendly stage, OPS2 changed once more; this time for its final time. Starting from issue 90 the magazine would focus on new PS2 owners and the younger gamer.